STUDIES ON MUTANTS OF BACILLUS SUBTILIS REQUIRING D-GLUTAMIC ACID
نویسندگان
چکیده
منابع مشابه
Mutants of Bacillus subtilis
Enzyme activities of glycolysis and glyconeogenesis are present in spores of Bacillus subtilis, the rate-limiting step of glucose (GLC) metabolism being its phosphorylation. GLC allows initiation of germination in the presence of fructose (FRU) and asparagine (ASN), not because it is used via the EmbdenMeyerhof path, but because it is oxidized in the nonphosphorylated form via the spore-specifi...
متن کاملGlutamine, glutamic acid, and glycolysis in Bacillus subtilis.
The effect of glutamic acid and glutamine on glycolysis is one of the few examples of a direct and apparently specific action of amino acids on a particular phase of carbohydrate metabolism. Glutamine has been shown to stimulate glycolysis in Streptococcus hemolyticus (1) and in iron-deficient cells of Clostridium tetuni (2). Glutamine, glutamic acid, and related compounds have also been report...
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A mutant of Bacillus subtilis 168 lacking aconitase (EC 4.2.1.3) was found to be blocked at stage 0 or I of sporulation. Although adenosine triphosphate levels, which normally decrease in tricarboxylic acid cycle mutants at the completion of exponential growth, could be maintained at higher levels by feeding metabolizable carbon sources, this did not permit the cells to progress further into th...
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Lipiarmycin inhibited the activity of deoxyribonucleic acid-dependent ribonucleic acid (RNA) polymerase in vitro. We showed that inhibition was due to interference by lipiarmycin with the activity of sigma-containing molecules of RNA polymerase. Transcription by core enzyme was relatively resistant to the drug, but addition of sigma led to highly drug-sensitive RNA synthesis. We isolated lipiar...
متن کاملDevelopmental block in citric acid cycle mutants of Bacillus subtilis.
Mutants deficient in different enzymes of the citric acid cycle can be subdivided into two groups according to the frequency at which they produce heat-resistant spores in nutrient sporulation medium. However, the majority of cells can develop in this medium only to the axial filament stage I of sporulation; aconitase and isocitrate dehydrogenase mutants need the addition of glutamate to reach ...
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ژورنال
عنوان ژورنال: The Journal of General and Applied Microbiology
سال: 1961
ISSN: 1349-8037,0022-1260
DOI: 10.2323/jgam.7.suppl1_370